What is PRP?
PRP (Platelet-Rich Plasma) is a regenerative aesthetic medicine treatment that uses the growth factors naturally present in your own blood to stimulate skin regeneration. The process begins with a blood draw — similar to a routine laboratory test — which is processed in a centrifuge to separate and concentrate the platelet-rich plasma, then applied to the skin via microinjections.
The underlying concept is elegant in its simplicity: platelets are not only involved in blood clotting — they release a battery of growth factors that the body uses to repair tissue. By concentrating them and returning them to the dermis, we give the skin a more intense "repair signal" than it would generate on its own. It is an autologous treatment: the injected material comes from the patient's own body, making the risk of allergic reaction or rejection very low.
Because your own plasma is used, PRP minimises the risk of allergic reactions or rejection. It is one of the treatments with the highest biocompatibility within aesthetic medicine. Even so, it is not free of contraindications — the prior consultation rules these out.
Unlike a filler, PRP does not provide immediate volume or "fill" a groove. Nor does it relax muscles like botulinum toxin. What it does is work on skin quality — texture, radiance, firmness, hydration — through stimulation of the body's own repair mechanisms. This is why it is typically integrated into a broader facial rejuvenation plan rather than used as a standalone treatment.
How does PRP work? (the mechanism)
To understand why PRP improves the skin progressively, it helps to follow the plasma's journey step by step — from blood draw to fibroblast activation:
1. Platelet concentration. After the blood draw, the blood is centrifuged to separate its components. The resulting plasma contains a platelet concentration several times higher than that of circulating blood. Within that concentrated fraction lie the growth factors of interest.
2. Growth factor release. When applied to the dermis, the platelets release signalling molecules including PDGF, TGF-β, VEGF, EGF, and IGF-1, among others. Each plays a role: stimulating fibroblasts, promoting the formation of new blood vessels (angiogenesis), and directing tissue repair.
3. Neocollagenesis (the progressive effect). These signals stimulate fibroblasts to produce type I and III collagen, elastin, and endogenous hyaluronic acid. This process — called neocollagenesis — is not immediate: it unfolds over the weeks following each session, which explains why results build gradually and naturally.
PRP does not produce an overnight change. It works by awakening the skin's own repair mechanisms, so improvement is appreciated gradually. The number of sessions and the timeline vary between patients and are evaluated at the consultation.
This regenerative logic is what distinguishes PRP from a filler: hyaluronic acid provides physical volume from the outside, while PRP stimulates the skin to produce its own structural support. This is why, in many cases, both treatments are planned in a complementary way.
Types and variants of PRP
"PRP" is a broad term: under this acronym exist different preparations depending on how the plasma is processed, what platelet concentration is targeted, and what white blood cell content it has. No variant is universally "better" — the indication depends on the goal of each area and medical judgement. The most commonly discussed in facial aesthetic medicine are:
- Classic PRP (Platelet-Rich Plasma): plasma with concentrated platelets in liquid form, applied via microinjections. The most common presentation for improving skin quality, radiance, and texture.
- P-PRP (poor in leucocytes): preparation with low white blood cell content, which some protocols prefer for facial treatments due to its milder profile.
- PRGF (Plasma Rich in Growth Factors): a specific protocol variant oriented towards maximising the controlled release of growth factors.
- PRP combined with microneedling: the plasma is applied alongside micropunctures to promote distribution and add the mechanical stimulus of microneedling to the skin.
An important distinction: PRP is not the same as so-called "gel PRP" or industrially manufactured biostimulators. PRP is always autologous — it comes from your own blood; other biostimulators are external products. The table below summarises, honestly, where the most commonly named variants differ. In all cases, timing and number of sessions are variable per patient and are evaluated at the consultation:
| Variant | Characteristic | Typical orientation |
|---|---|---|
| Classic PRP Most used | Concentrated platelet plasma, autologous | Skin quality, radiance, and facial texture |
| P-PRP (leucocyte-poor) | Low white blood cell content | Facial treatments with a milder profile |
| PRGF | Protocol oriented towards growth factors | Controlled regenerative stimulation |
| PRP + microneedling | Plasma combined with micropunctures | Texture, pores, and even distribution |
Dra. Jenny defines the preparation, the number of sessions, and the areas to treat during the evaluation consultation, based on each patient's skin condition, goals, and medical history.
Treatment areas and indications
PRP stimulates the skin's natural regeneration mechanisms, so its effect builds session by session. Below are the areas and indications where it is most commonly used. The intensity and timeline of the response vary between patients:
Because of its regenerative nature, PRP is typically perceived gradually: many patients first notice an improvement in radiance and texture, and then, over the following weeks, changes in firmness. The pace of improvement and the number of sessions vary between patients and are evaluated at the consultation, based on skin condition and goals.
Who is a candidate? (and when they are not)
PRP facial treatment is an option to consider for a wide range of patients who seek to improve their skin quality naturally, without resorting to more invasive procedures. It is typically indicated for:
- Patients with dull or fatigued skin who want to restore radiance naturally.
- People with uneven texture, enlarged pores, or superficial acne scars.
- Those seeking a preventive and regenerative approach to the first signs of ageing.
- Patients with vascular or pigmentation dark circles in the periorbital area.
- People who prefer autologous treatments — using their own plasma, with no external products.
- Those wishing to complement other treatments — hyaluronic acid, botulinum toxin, or peels — within a single plan.
When is PRP not the best option?
Being honest also means saying when this treatment is not indicated or is not appropriate. PRP is not recommended for:
- Patients with clotting disorders or those on anticoagulant therapy.
- Active infections in the area to be treated or systemic infections.
- Active autoimmune diseases or other haematological conditions that contraindicate it.
- Pregnancy and breastfeeding, during which the treatment is preferred to be postponed.
- Patients seeking volume correction or an immediate "lifting" effect: in cases of marked laxity or volume loss, PRP alone is not the appropriate tool, and fillers, threads, or surgery should be evaluated depending on the case.
This is why the evaluation consultation is indispensable: it rules out contraindications, aligns expectations, and — if PRP is not the most appropriate option — says so clearly and proposes the alternative that best meets your goals.
The procedure, step by step
The PRP facial protocol at Dra. Jenny Ortega De La Rosa's practice is as follows:
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1
Blood draw A small amount of blood (10–20 ml) is drawn from the patient's arm, exactly as in a routine laboratory test. The procedure takes under 2 minutes.
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2
Centrifugation and plasma preparation The blood is processed in a specialised centrifuge for 8–10 minutes. This separates the blood components and concentrates the platelets in the plasma, achieving a concentration 3 to 5 times higher than that of normal blood.
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3
Topical anaesthesia While the blood is being centrifuged, an anaesthetic cream is applied to the treatment area. This acts during the 20–30 minutes of the centrifugation process, minimising discomfort from the microinjections.
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4
Plasma microinjections The concentrated plasma is injected into the dermis via multiple microinjections distributed evenly across the treatment areas (face, neck, décolletage, eye contour). The procedure takes 20–30 minutes.
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5
Close and immediate aftercare instructions There is typically mild redness and swelling that tends to subside within the first 24–48 hours. Most patients resume their daily activities the same day or the day after. Aftercare instructions are provided and a follow-up appointment is scheduled.
Aftercare and recovery
One of the advantages of PRP is its typically brief recovery: as microinjections of your own plasma are used, no prolonged rest is required and most patients return to their routine the same day or the day after. Supporting the process with simple aftercare contributes to a better outcome.
What to expect in the first hours
It is normal to experience mild redness, a sensation of warmth, and some swelling at the injection points, and occasionally small bruises that resolve on their own. These discomforts are typically mild and tend to subside within 24–72 hours. Intensity varies between patients and the area treated.
Recommendations for the first few days
- Avoid make-up and contact with the treated area during the first hours, as instructed.
- Do not expose yourself to direct sun and use sun protection to support skin regeneration.
- Avoid intense physical activity, saunas, and swimming pools on the first day or as instructed.
- Avoid alcohol and, where possible, non-prescribed anti-inflammatories, as they can interfere with the regenerative process.
- Maintain good hydration and a gentle skincare routine in the days following the procedure.
Although complications are uncommon, in the event of intense pain that does not subside, signs of infection (increasing heat and redness, discharge), or any reaction that concerns you, contact the practice. The post-procedure follow-up allows the progress to be assessed and any questions to be resolved.
Enquire about PRP facial treatment
We assess your skin and design the most suitable protocol for your goals.
Contact via WhatsAppPRP vs other options
PRP is not the only rejuvenation treatment, and it does not compete with the rest: in general they complement one another. Each one addresses a different concern more effectively. Understanding what each option does helps to make an informed choice and avoid misaligned expectations:
| Option | Best suited for | Type of action | Recovery |
|---|---|---|---|
| PRP Regenerative | Skin quality: radiance, texture, firmness | Collagen stimulation (progressive, autologous) | Typically brief |
| Mesotherapy | Skin hydration and nourishment | Supply of vitamins and external actives | Minimal |
| Hyaluronic acid | Volume loss and grooves; does not regenerate | Immediate physical filler | Minimal |
| Botulinum toxin | Dynamic expression lines; does not treat texture | Muscle relaxation | No downtime |
| Skinboosters | Deep and sustained skin hydration | Low molecular weight hyaluronic acid | Minimal |
In practice, PRP tends to be integrated with other treatments rather than replacing them. A common planning approach combines PRP — which addresses skin quality — with hyaluronic acid to restore volume and with botulinum toxin to soften dynamic expression lines. What is combined, in what order, and at what intervals is determined at the evaluation consultation.
PRP does not seek to replace a filler or botulinum toxin — it acts on a different aspect of rejuvenation. When there is marked laxity or excess skin, PRP alone is not the appropriate tool and threads or surgery may need to be evaluated. The consultation determines the most appropriate plan for each individual case.
Cost in Buenos Aires
The fee for PRP facial treatment is defined at the valuation consultation with Dra. Jenny Ortega De La Rosa, based on the treatment area, the number of sessions indicated, and skin condition. As a personalised medical service, we do not publish prices:
- Evaluation consultation and treatment plan design
- Blood draw and plasma centrifugation
- Topical anaesthesia included
- Microinjections to face, neck, and/or décolletage
- Personalised plan according to skin type
- Post-procedure follow-up appointment
PRP is typically planned as a series of sessions spaced over time, with possible maintenance sessions afterwards. The exact number of sessions, intervals, and the possibility of combining it with other treatments are tailored to each patient's skin condition and goals, and are always defined at the valuation consultation.
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View in Treatments →Frequently asked questions about PRP
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