PRP · Platelet-Rich Plasma

What is PRP?

PRP (Platelet-Rich Plasma) is a regenerative aesthetic medicine treatment that uses the growth factors naturally present in your own blood to stimulate skin regeneration. The process begins with a blood draw — similar to a routine laboratory test — which is processed in a centrifuge to separate and concentrate the platelet-rich plasma, then applied to the skin via microinjections.

The underlying concept is elegant in its simplicity: platelets are not only involved in blood clotting — they release a battery of growth factors that the body uses to repair tissue. By concentrating them and returning them to the dermis, we give the skin a more intense "repair signal" than it would generate on its own. It is an autologous treatment: the injected material comes from the patient's own body, making the risk of allergic reaction or rejection very low.

Autologous — high biocompatibility

Because your own plasma is used, PRP minimises the risk of allergic reactions or rejection. It is one of the treatments with the highest biocompatibility within aesthetic medicine. Even so, it is not free of contraindications — the prior consultation rules these out.

Unlike a filler, PRP does not provide immediate volume or "fill" a groove. Nor does it relax muscles like botulinum toxin. What it does is work on skin quality — texture, radiance, firmness, hydration — through stimulation of the body's own repair mechanisms. This is why it is typically integrated into a broader facial rejuvenation plan rather than used as a standalone treatment.

How does PRP work? (the mechanism)

To understand why PRP improves the skin progressively, it helps to follow the plasma's journey step by step — from blood draw to fibroblast activation:

1. Platelet concentration. After the blood draw, the blood is centrifuged to separate its components. The resulting plasma contains a platelet concentration several times higher than that of circulating blood. Within that concentrated fraction lie the growth factors of interest.

2. Growth factor release. When applied to the dermis, the platelets release signalling molecules including PDGF, TGF-β, VEGF, EGF, and IGF-1, among others. Each plays a role: stimulating fibroblasts, promoting the formation of new blood vessels (angiogenesis), and directing tissue repair.

3. Neocollagenesis (the progressive effect). These signals stimulate fibroblasts to produce type I and III collagen, elastin, and endogenous hyaluronic acid. This process — called neocollagenesis — is not immediate: it unfolds over the weeks following each session, which explains why results build gradually and naturally.

Progressive effect, not immediate

PRP does not produce an overnight change. It works by awakening the skin's own repair mechanisms, so improvement is appreciated gradually. The number of sessions and the timeline vary between patients and are evaluated at the consultation.

This regenerative logic is what distinguishes PRP from a filler: hyaluronic acid provides physical volume from the outside, while PRP stimulates the skin to produce its own structural support. This is why, in many cases, both treatments are planned in a complementary way.

Types and variants of PRP

"PRP" is a broad term: under this acronym exist different preparations depending on how the plasma is processed, what platelet concentration is targeted, and what white blood cell content it has. No variant is universally "better" — the indication depends on the goal of each area and medical judgement. The most commonly discussed in facial aesthetic medicine are:

An important distinction: PRP is not the same as so-called "gel PRP" or industrially manufactured biostimulators. PRP is always autologous — it comes from your own blood; other biostimulators are external products. The table below summarises, honestly, where the most commonly named variants differ. In all cases, timing and number of sessions are variable per patient and are evaluated at the consultation:

Variant Characteristic Typical orientation
Classic PRP Most used Concentrated platelet plasma, autologous Skin quality, radiance, and facial texture
P-PRP (leucocyte-poor) Low white blood cell content Facial treatments with a milder profile
PRGF Protocol oriented towards growth factors Controlled regenerative stimulation
PRP + microneedling Plasma combined with micropunctures Texture, pores, and even distribution

Dra. Jenny defines the preparation, the number of sessions, and the areas to treat during the evaluation consultation, based on each patient's skin condition, goals, and medical history.

Treatment areas and indications

PRP stimulates the skin's natural regeneration mechanisms, so its effect builds session by session. Below are the areas and indications where it is most commonly used. The intensity and timeline of the response vary between patients:

Radiance
Progressive improvement in skin brightness and vitality. Natural "skin glow" effect.
Texture
Refinement of skin texture, reduction of enlarged pores, and improvement of superficial scars.
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Firmness
Collagen and elastin stimulation that contributes progressively to firmer, more compact skin.
Hydration
Improved capacity to retain moisture. A more hydrated, plump appearance sustained over time.
Dark circles
Improvement of vascular and pigmentation dark circles through regeneration of delicate periorbital skin.
Fine lines
Softening of superficial fine lines by stimulating cellular renewal and natural collagen-based filling.

Because of its regenerative nature, PRP is typically perceived gradually: many patients first notice an improvement in radiance and texture, and then, over the following weeks, changes in firmness. The pace of improvement and the number of sessions vary between patients and are evaluated at the consultation, based on skin condition and goals.

Who is a candidate? (and when they are not)

PRP facial treatment is an option to consider for a wide range of patients who seek to improve their skin quality naturally, without resorting to more invasive procedures. It is typically indicated for:

When is PRP not the best option?

Being honest also means saying when this treatment is not indicated or is not appropriate. PRP is not recommended for:

This is why the evaluation consultation is indispensable: it rules out contraindications, aligns expectations, and — if PRP is not the most appropriate option — says so clearly and proposes the alternative that best meets your goals.

The procedure, step by step

The PRP facial protocol at Dra. Jenny Ortega De La Rosa's practice is as follows:

  1. 1
    Blood draw A small amount of blood (10–20 ml) is drawn from the patient's arm, exactly as in a routine laboratory test. The procedure takes under 2 minutes.
  2. 2
    Centrifugation and plasma preparation The blood is processed in a specialised centrifuge for 8–10 minutes. This separates the blood components and concentrates the platelets in the plasma, achieving a concentration 3 to 5 times higher than that of normal blood.
  3. 3
    Topical anaesthesia While the blood is being centrifuged, an anaesthetic cream is applied to the treatment area. This acts during the 20–30 minutes of the centrifugation process, minimising discomfort from the microinjections.
  4. 4
    Plasma microinjections The concentrated plasma is injected into the dermis via multiple microinjections distributed evenly across the treatment areas (face, neck, décolletage, eye contour). The procedure takes 20–30 minutes.
  5. 5
    Close and immediate aftercare instructions There is typically mild redness and swelling that tends to subside within the first 24–48 hours. Most patients resume their daily activities the same day or the day after. Aftercare instructions are provided and a follow-up appointment is scheduled.

Aftercare and recovery

One of the advantages of PRP is its typically brief recovery: as microinjections of your own plasma are used, no prolonged rest is required and most patients return to their routine the same day or the day after. Supporting the process with simple aftercare contributes to a better outcome.

What to expect in the first hours

It is normal to experience mild redness, a sensation of warmth, and some swelling at the injection points, and occasionally small bruises that resolve on their own. These discomforts are typically mild and tend to subside within 24–72 hours. Intensity varies between patients and the area treated.

Recommendations for the first few days

Signs that warrant consultation

Although complications are uncommon, in the event of intense pain that does not subside, signs of infection (increasing heat and redness, discharge), or any reaction that concerns you, contact the practice. The post-procedure follow-up allows the progress to be assessed and any questions to be resolved.

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PRP vs other options

PRP is not the only rejuvenation treatment, and it does not compete with the rest: in general they complement one another. Each one addresses a different concern more effectively. Understanding what each option does helps to make an informed choice and avoid misaligned expectations:

Option Best suited for Type of action Recovery
PRP Regenerative Skin quality: radiance, texture, firmness Collagen stimulation (progressive, autologous) Typically brief
Mesotherapy Skin hydration and nourishment Supply of vitamins and external actives Minimal
Hyaluronic acid Volume loss and grooves; does not regenerate Immediate physical filler Minimal
Botulinum toxin Dynamic expression lines; does not treat texture Muscle relaxation No downtime
Skinboosters Deep and sustained skin hydration Low molecular weight hyaluronic acid Minimal

In practice, PRP tends to be integrated with other treatments rather than replacing them. A common planning approach combines PRP — which addresses skin quality — with hyaluronic acid to restore volume and with botulinum toxin to soften dynamic expression lines. What is combined, in what order, and at what intervals is determined at the evaluation consultation.

They complement each other, not compete

PRP does not seek to replace a filler or botulinum toxin — it acts on a different aspect of rejuvenation. When there is marked laxity or excess skin, PRP alone is not the appropriate tool and threads or surgery may need to be evaluated. The consultation determines the most appropriate plan for each individual case.

Cost in Buenos Aires

The fee for PRP facial treatment is defined at the valuation consultation with Dra. Jenny Ortega De La Rosa, based on the treatment area, the number of sessions indicated, and skin condition. As a personalised medical service, we do not publish prices:

Investment per session
Upon consultation
The fee is defined at the valuation consultation, based on the area, number of sessions, and skin condition.
  • Evaluation consultation and treatment plan design
  • Blood draw and plasma centrifugation
  • Topical anaesthesia included
  • Microinjections to face, neck, and/or décolletage
  • Personalised plan according to skin type
  • Post-procedure follow-up appointment

PRP is typically planned as a series of sessions spaced over time, with possible maintenance sessions afterwards. The exact number of sessions, intervals, and the possibility of combining it with other treatments are tailored to each patient's skin condition and goals, and are always defined at the valuation consultation.

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Frequently asked questions about PRP

PRP is platelet-rich plasma obtained from your own blood. A small blood draw is performed — similar to a routine laboratory test — the blood is centrifuged to concentrate the platelets, and that plasma — loaded with growth factors — is applied to the skin via microinjections. Because it is autologous, meaning derived from your own body, its biocompatibility profile is high and the risk of allergic reaction or rejection is very low.
A topical anaesthetic cream is applied before the procedure, which minimises discomfort. The sensation during microinjections is typically described as small, mild pinpricks, and the blood draw is identical to a routine laboratory test. Tolerance varies between patients, but the majority report manageable discomfort.
PRP is typically planned as a series of sessions spaced over time, with possible maintenance sessions afterwards. The exact number and intervals vary between patients and are determined at the consultation, based on skin condition and goals. We do not publish a fixed number because it depends on each individual case.
PRP works by stimulating the skin's own repair mechanisms, so its effect is progressive rather than immediate. Many patients first notice an improvement in radiance and texture, and later changes in firmness. The timeline varies between patients and is evaluated at the consultation and follow-up appointments.
No. PRP is not a filler and does not provide immediate physical volume. Its function is to improve skin quality — texture, radiance, firmness, and hydration — by stimulating the body's own collagen production. When the goal is to restore volume or correct deeper grooves, hyaluronic acid is the appropriate tool. In many cases both are planned in a complementary way, which is evaluated at the consultation.
Mesotherapy uses externally formulated cocktails of vitamins, minerals, and low-molecular-weight hyaluronic acid injected into the skin. PRP uses the patient's own plasma with its growth factors, making it an autologous treatment. Mesotherapy acts primarily at a nutritional and hydration level, while PRP has a more regenerative orientation. They are complementary and can be combined.
Yes. PRP is part of facial rejuvenation protocols and is commonly combined with hyaluronic acid (to restore volume) and with botulinum toxin (for dynamic expression lines). Each treatment addresses a different aspect of ageing, so the combination contributes to a more complete result. What is combined, in what order, and at what intervals is determined at the consultation.
PRP is not indicated for patients with clotting disorders, those on anticoagulant therapy, with active infections in the treatment area, with active autoimmune or haematological diseases, or during pregnancy and breastfeeding. It is also not the best option when the goal is immediate volume correction or lifting. The prior consultation rules out contraindications and, if PRP is not the most appropriate option, an alternative that better meets the patient's goals is proposed.
Recovery is typically brief. Mild redness, warmth, and some swelling at the injection points are normal, and occasionally small bruises that resolve on their own; these tend to subside within 24–72 hours. Most patients resume their routine the same day or the day after. It is advisable to avoid direct sun exposure, use sun protection, and follow the aftercare instructions provided. Intensity varies between patients.
The fee is defined at the valuation consultation with Dra. Jenny, based on each patient's needs. As a personalised medical service, we do not publish prices — everything is arranged at the initial consultation, where the session plan is also determined according to skin condition and each patient's goals.
Dra. Jenny Ortega De La Rosa · Buenos Aires

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