Exosomes
in Buenos Aires

Exosomes are nanometric extracellular vesicles (30–150 nm) produced by stem cells. They act as intercellular messengers that transport proteins, RNA and biological signals instructing recipient cells to activate regeneration processes, collagen production and inflammation reduction. They are considered an advanced therapeutic line within regenerative medicine, with a specific mechanism of action.

PRP uses growth factors from the patient's own blood, while exosomes are nanometric vesicles loaded with regeneration signals derived from stem cells. Exosomes act on regeneration mechanisms and do not require a blood draw, with an effect whose duration varies from patient to patient. Additionally, the Skinretin Xpert protocol combines exosomes with retinol, vitamin C and hyaluronic acid for a multifactorial action.

The Skinretin Xpert protocol is generally applied in cycles of 3 to 4 sessions, spaced every 2 to 4 weeks. Results are progressive and consolidate in the weeks following each session. For cases of advanced aging or very damaged skin, a second cycle per year may be indicated. Dr. Jenny personalizes the number of sessions based on the skin condition and each patient's goals.

Exosome treatment is especially indicated for patients with signs of skin aging, sun-damaged skin, skin following procedures such as peels or laser, pigmentation concerns and melasma, and sensitive or reactive skin. It is also ideal as a post-surgical complement to accelerate recovery from facial surgeries. It has no major contraindications and is well tolerated by almost all skin types.

The application is performed in the clinic and usually takes about 60 minutes. Depending on the protocol indicated for each skin type, the Skinretin Xpert preparation is applied with microneedling, superficial mesotherapy or enhanced transdermal absorption techniques, so that the exosomes reach the dermal layers where fibroblasts act. The specific technique is defined during the evaluation consultation.

It is a well-tolerated treatment. When performed with microneedling, mild discomfort may be felt, which is minimized with prior topical anesthesia. In the hours following the session, the skin may show mild redness or a sensation of warmth that resolves on its own. No rest is required and most patients resume their activities on the same day.

Exosomes work on skin quality and their effect is progressive: collagen regeneration and improvement in texture and radiance build over the weeks following each session and consolidate throughout the cycle. It is not an immediate-effect treatment like a filler. The pace and extent of improvement vary from patient to patient and are evaluated during the consultation.

During the first few days, strict sun protection is recommended (5–7 days), avoiding direct sun exposure, sauna and swimming pools, and suspending strong acids, home-use retinoids and exfoliants for 48–72 hours. Keep the skin clean and hydrated, and postpone makeup for the first few hours if the application was with microneedling. Cycle follow-up is included.

No — they solve different things and complement each other. Exosomes improve skin quality (texture, firmness, radiance) and support post-procedure recovery, but they do not add volume or lift structures. For volume there is hyaluronic acid; for mild to moderate laxity, thread lifts; and when there is severe laxity or excess skin, surgical lifting offers a clearly superior result. The consultation determines the best combination for each case.

It is not indicated during pregnancy and breastfeeding, in the presence of active infections or lesions in the treatment area, in autoimmune diseases or active oncological processes without authorization from the treating physician, or in cases of known allergy to any component of the preparation. The prior evaluation consultation reviews your medical history and determines whether exosomes are the most suitable option for your case.